{"product_id":"adrenal-synergy","title":"Adrenal Synergy","description":"\u003ch1 class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eAdrenal Synergy\u003c\/strong\u003e \u003c\/h1\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eis a comprehensive adrenal and HPA axis support formula combining four standardized adaptogenic botanicals, five bovine and porcine glandular extracts, adrenal-specific vitamins and minerals, and Alpha Lipoic Acid in a single daily two-capsule serving, designed to nourish the neuro-endocrine pathways that govern stress resilience, energy, mood, immune function, hormonal balance, and metabolic stability.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eThe adrenal glands and the HPA (hypothalamic-pituitary-adrenal) axis form the central command system of the body's stress response. When cortisol is called upon repeatedly and the adrenal glands cannot keep pace with demand, the downstream consequences extend far beyond fatigue. Thyroid hormone conversion slows. Immune surveillance weakens. Sleep architecture deteriorates. Hormonal production declines. Mood becomes fragile. Blood sugar regulation destabilizes. And the body's capacity to recover from the next stressor is reduced, creating a cycle of progressive depletion that most single-ingredient adrenal supplements cannot adequately address.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eAdrenal Synergy was formulated for this complexity. The four adaptogens, Ashwagandha, Rhodiola, Eleuthero, and Asian Ginseng, each work through distinct mechanisms on the HPA axis to modulate the stress response, support adrenal cortical function, and rebuild resilience over time. The glandular complex, including Suprarenal Adrenal (Porcine), Suprarenal Cortex (Bovine), Pituitary (Bovine), Hypothalamus (Bovine), and Thymus (Bovine), provides direct glandular tissue support through the nutritional and signaling compounds naturally concentrated in these organs, a cornerstone of glandular therapy used in integrative and functional medicine for decades. The nutrient matrix, Vitamin C, B6 as P5P, Methylfolate, Pantothenic Acid, and Zinc, directly nourishes the adrenal tissue and enzymatic pathways involved in cortisol and catecholamine synthesis. And the DGL Licorice and Alpha Lipoic Acid round out the formula with cortisol-modulating and antioxidant support.Contains porcine and bovine glandular extracts. Not suitable for those avoiding animal-derived ingredients. Non-GMO. Gluten-free. Vegetable capsule (hypromellose). 60 capsules, 30 servings at 2 capsules daily.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eKey Benefits:\u003c\/strong\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy adrenal gland function and HPA axis balance\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePromotes healthy cortisol metabolism and balanced stress response\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports sustained energy and reduced stress-related exhaustion\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy mood, cognitive clarity, and emotional resilience under stress\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePromotes healthy immune function via thymus glandular support\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy hypothalamic-pituitary signaling for neuro-endocrine balance\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy thyroid function indirectly via HPA axis regulation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy sleep quality by addressing adrenal-driven cortisol dysregulation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy hormonal production and balance\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy blood sugar and metabolic stability under stress\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eFour standardized adaptogenic botanicals address the stress response through distinct and complementary pathways\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eFive glandular extracts provide direct adrenal, pituitary, hypothalamus, and thymus support\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eActive nutrient matrix including P5P, Methylfolate, and Pantothenic Acid directly nourishes adrenal tissue\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eVegetable capsule, non-GMO, gluten-free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eWhat's Inside — Full Supplement Facts (per 2-capsule serving):\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eVitamin C (as Ascorbic Acid) — 50 mg\u003c\/strong\u003e — The adrenal glands contain the highest concentration of Vitamin C in the body. Vitamin C is required for cortisol synthesis and is rapidly depleted during acute and chronic stress. Replenishing Vitamin C supports adrenal tissue health and cortisol production capacity.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eVitamin B6 (as Pyridoxal-5-Phosphate) — 1 mg\u003c\/strong\u003e — The active coenzyme form of B6. Essential for adrenal catecholamine synthesis, including the enzymatic conversion of tyrosine to dopamine, norepinephrine, and epinephrine, the stress hormones produced by the adrenal medulla.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eFolate (as Methyltetrahydrofolic Acid) — 50 mcg\u003c\/strong\u003e — Active methylfolate supporting the methylation cycle that drives adrenal hormone metabolism, healthy homocysteine processing, and neurotransmitter synthesis.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003ePantothenic Acid (as d-Calcium Pantothenate) — 50 mg\u003c\/strong\u003e — The single most essential B vitamin for adrenal function. Pantothenic Acid is required for Coenzyme A synthesis, the central cofactor for steroid hormone production in the adrenal cortex.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eZinc (as Zinc AAC) — 1 mg\u003c\/strong\u003e — An essential cofactor for adrenal enzyme activity, immune function, and the antioxidant defense systems that protect adrenal tissue from the oxidative burden of cortisol synthesis.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eSuprarenal Adrenal (Porcine) — 50 mg\u003c\/strong\u003e — Porcine adrenal glandular extract providing the naturally occurring nutritional and signaling compounds concentrated in adrenal tissue. Used in glandular therapy to provide direct adrenal support through the tissue-specific compounds that support adrenal function and recovery.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eSuprarenal Cortex (Bovine) — 100 mg\u003c\/strong\u003e — Bovine adrenal cortex extract providing the cortical layer of the adrenal gland, which is responsible for cortisol, aldosterone, and DHEA production. Adrenal cortex glandular has a longer history of use in functional medicine than whole adrenal glandular for supporting cortisol pathway recovery.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eOrganic Ashwagandha Root Extract (standardized 5% withanolides) — 100 mg\u003c\/strong\u003e — A premier adaptogen supporting healthy HPA axis function, cortisol modulation, thyroid hormone T4-to-T3 conversion, and adrenal recovery during periods of sustained demand.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003ePituitary (Bovine) — 100 mg\u003c\/strong\u003e — Bovine anterior pituitary glandular extract providing support for the pituitary gland's signaling role in the HPA axis. The pituitary produces ACTH (adrenocorticotropic hormone), which signals the adrenals to produce cortisol, and pituitary glandular is used in integrative medicine to support healthy HPA axis signaling capacity.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eRhodiola Root Extract (standardized 3% Rosavin, 1% Salidroside) — 100 mg\u003c\/strong\u003e — A Scandinavian and Siberian adaptogen extensively studied for HPA axis modulation, stress resilience, cognitive performance under stress, anti-fatigue activity, and mitochondrial energy support. The standardized rosavin and salidroside content ensures consistent adaptogenic activity.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eLicorice Root DGL Extract (standardized 3.0% Glycyrrhizinic Acid) — 75 mg\u003c\/strong\u003e — Deglycyrrhizinated licorice providing cortisol-modulating activity by inhibiting the enzyme (11-beta-HSD2) that breaks down cortisol, effectively extending the half-life of available cortisol and reducing adrenal demand. Particularly supportive during low-cortisol phases of HPA axis dysregulation.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eEleuthero Root Extract (standardized 0.8% Eleutheroside) — 50 mg\u003c\/strong\u003e — Siberian ginseng providing HPA axis modulation, enhanced physical and mental endurance, immune support, and adrenal resilience through a distinct mechanism from Ashwagandha and Rhodiola.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eAsian Ginseng Aerial Parts (standardized 8% Ginsenosides) — 50 mg\u003c\/strong\u003e — An adaptogen supporting healthy HPA axis function, physical and cognitive performance under stress, and the regeneration of hypothalamic cortisol receptor sensitivity for improved self-regulation of cortisol levels.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eHypothalamus (Bovine) — 50 mg\u003c\/strong\u003e — Bovine hypothalamus glandular extract supporting the hypothalamic regulation of the HPA axis, including the production of CRH (corticotropin-releasing hormone) that initiates the cortisol cascade.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eThymus (Bovine) — 30 mg\u003c\/strong\u003e — Bovine thymus glandular extract supporting immune function and immune resilience. The thymus is the primary site of T-cell maturation and immune education, and thymus glandular is used in integrative medicine to support immune capacity that is frequently compromised by adrenal-driven cortisol dysregulation.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eAlpha Lipoic Acid — 5 mg\u003c\/strong\u003e — A universal antioxidant active in both water and fat-soluble environments that supports adrenal tissue protection from oxidative stress and complements the glutathione-recycling activity needed during periods of high adrenal demand.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eOther Ingredients:\u003c\/strong\u003e Hypromellose (vegetable capsule), Microcrystalline Cellulose, Certified Organic Rice Extract (organic rice hulls, organic gum arabic, organic sunflower oil, silica).\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cstrong\u003eStorage\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eStore in a cool, dry, tightly closed place. Keep out of reach of children.\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cstrong\u003eDirections\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eTake 2 capsules daily with meals, or as directed by your healthcare professional.If you are under 18, pregnant, nursing, taking medications, or have a medical condition, consult your healthcare practitioner before use. Contains porcine and bovine glandular extracts.\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cem\u003e\u003c\/em\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003e\u003cmeta charset=\"utf-8\"\u003eAdrenal Synergy by DesBio is a practitioner-formulated adrenal and HPA axis support supplement available at SOLUDE Wellness \u0026amp; Beauty. It contains Vitamin C 50 mg, Vitamin B6 (as P5P) 1 mg, Folate (as Methyltetrahydrofolic Acid) 50 mcg, Pantothenic Acid 50 mg, Zinc (as Zinc AAC) 1 mg, Suprarenal Adrenal (Porcine) 50 mg, Suprarenal Cortex (Bovine) 100 mg, Organic Ashwagandha Root Extract (5% withanolides) 100 mg, Pituitary (Bovine) 100 mg, Rhodiola Root Extract (3% Rosavin, 1% Salidroside) 100 mg, Licorice Root DGL Extract (3.0% Glycyrrhizinic Acid) 75 mg, Eleuthero Root Extract (0.8% Eleutheroside) 50 mg, Asian Ginseng Aerial Parts (8% Ginsenosides) 50 mg, Hypothalamus (Bovine) 50 mg, Thymus (Bovine) 30 mg, and Alpha Lipoic Acid 5 mg, in a vegetable capsule with organic rice extract. It is designed to support healthy adrenal function and HPA axis balance, cortisol metabolism and stress resilience, sustained energy, mood stability, immune function, thyroid support, sleep quality, and hormonal balance. Contains porcine and bovine glandulars. Non-GMO, gluten-free. 60 capsules, 30 servings. Take 2 capsules daily with meals.\u003c\/em\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003e\u003c\/em\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003eThese statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/div\u003e","brand":"DesBio","offers":[{"title":"Default Title","offer_id":45534406115372,"sku":"SLD-DSB-ADRS-60","price":41.69,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0617\/6122\/4748\/files\/AdrenalSynergy-DesBio.png?v=1778527180","url":"https:\/\/soludebewell.com\/products\/adrenal-synergy","provider":"Solude","version":"1.0","type":"link"}