{"product_id":"desbio-liposomal-calm-gaba-theanine-5htp-stress-relief","title":"Liposomal Calm","description":"\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003ch1 class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cstrong\u003eLiposomal Calm\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h1\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eis a concentrated liquid stress relief and relaxation formula delivering a proprietary blend of six clinically relevant calming amino acids and botanicals, including PharmaGABA, L-Theanine, 5-HTP, Passionflower, Holy Basil, and Dwarf Morning Glory Root, alongside Vitamin B6 and Glycine, in a non-GMO phosphatidylcholine liposomal delivery system for rapid, superior absorption directly into the nervous system, without sedation, drowsiness, or dependence.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eChronic stress does not resolve on its own. When the nervous system is locked in a prolonged activation state, the physiological consequences accumulate: cortisol stays elevated, GABA becomes depleted, serotonin production is disrupted, sleep quality deteriorates, and the threshold for feeling calm, safe, and grounded keeps rising. Most people in this state are not sleeping their way out of it, exercising their way out of it, or supplementing their way out of it with a single ingredient. They need a multi-pathway approach that addresses the neurochemistry of stress at several levels simultaneously.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eLiposomal Calm does exactly this. PharmaGABA provides the primary inhibitory neurotransmitter the nervous system depends on to downshift from excitatory activation. L-Theanine promotes alpha brain wave activity for calm, alert focus without drowsiness. 5-HTP provides the direct precursor to serotonin, the mood-regulating neurotransmitter that chronic stress consistently depletes. Passionflower, Holy Basil, and Dwarf Morning Glory Root address the botanical layer of the formula through their own complementary calming and adaptogenic mechanisms. Vitamin B6 as pyridoxal-5-phosphate ensures the enzymatic conversion of all amino acid precursors proceeds efficiently. Glycine provides its own CNS inhibitory activity alongside structural benefits for collagen and gut lining.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eThe liposomal phosphatidylcholine delivery system is what distinguishes this formula from capsule-based GABA and amino acid supplements. Standard oral GABA and amino acid supplements face significant absorption challenges and do not efficiently cross the blood-brain barrier in standard capsule form. Liposomal encapsulation in phospholipid vesicles that mirror cell membrane structure enables direct mucosal absorption, bypassing the digestive breakdown that limits standard supplementation and allowing the active ingredients to reach the nervous system with measurably faster and more complete bioavailability.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eChocolate flavor. Non-GMO sunflower lecithin base. 6 oz bottle, approximately 12 servings at 15 mL daily. Refrigerate after opening.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003eKey Benefits:\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports feelings of calm and relaxation without sedation or drowsiness\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePromotes healthy GABA activity via PharmaGABA for nervous system downregulation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy serotonin production via 5-HTP for mood stability and emotional resilience\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports alpha brain wave activity via L-Theanine for calm, focused mental clarity\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports healthy stress response via Holy Basil adaptogenic activity\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSupports the nervous system during periods of elevated anxiety and mental overactivation\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePromotes relaxation and sleep readiness when taken in the evening\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eVitamin B6 as pyridoxal-5-phosphate supports efficient amino acid conversion throughout the formula\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eGlycine provides additional CNS inhibitory neurotransmitter calming activity\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eLiposomal phosphatidylcholine delivery for superior absorption vs standard capsule-based GABA supplements\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eNon-habit forming and non-sedating at recommended doses\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eChocolate flavored liquid that mixes easily into any beverage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eWhat's Inside — Full Supplement Facts (per 15 mL serving):\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eVitamin B6 (as Pyridoxal-5-Phosphate) — 1 mg\u003c\/strong\u003e — The active, pre-converted coenzyme form of B6. Included specifically as the enzymatic cofactor for amino acid conversion reactions throughout this formula, including the conversion of 5-HTP to serotonin, the synthesis of GABA from glutamate, and the decarboxylation reactions that activate the formula's amino acid blend. P5P ensures these conversions occur efficiently without the additional conversion step required by standard pyridoxine forms.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eGlycine — 200 mg\u003c\/strong\u003e — An inhibitory neurotransmitter in the brainstem and spinal cord that works alongside GABA to provide complementary CNS calming activity. Glycine supports relaxation, body temperature regulation for sleep readiness, and the overall inhibitory tone that a chronically activated nervous system requires to genuinely downshift. Also supports collagen synthesis and gut lining integrity as secondary structural benefits.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eLiposomal Calm Blend — 245 mg (total):\u003c\/strong\u003e\u003cstrong\u003eL-Theanine\u003c\/strong\u003e — An amino acid found naturally in green tea that promotes alpha brain wave activity, the calm, alert state that precedes natural focus and sleep readiness, without inducing sedation or impairing cognitive function. L-Theanine reduces the mental overactivation and anxious tension that characterize a nervous system locked in sympathetic dominance, working synergistically with GABA to provide two complementary pathways of calming support.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003ePassionflower Herb Extract (Passiflora incarnata)\u003c\/strong\u003e — A traditional botanical with a centuries-long history of use for nervous system calming and anxiety relief. Passionflower supports GABA-ergic neurotransmission through a mechanism distinct from GABA itself, providing complementary botanical support for nervous system downregulation that is well-tolerated and non-habit forming.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eHoly Basil Leaf Extract (Ocimum sanctum)\u003c\/strong\u003e — An Ayurvedic adaptogenic herb, also known as Tulsi, with clinical research supporting its role in healthy cortisol regulation, HPA axis balance, cognitive performance under stress, and antioxidant protection of neural tissue. Holy Basil provides the adaptogenic layer of the formula, helping the body adapt to and recover from the chronic stress burden that underlies most cases of elevated anxiety and depleted calm.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eGABA (as PharmaGABA) — Gamma-Aminobutyric Acid\u003c\/strong\u003e — PharmaGABA is a patented, naturally fermented form of GABA produced by Lactobacillus hilgardii bacteria, the same bacteria used in the production of traditional Korean kimchi. PharmaGABA has been specifically studied for its superior bioavailability and brain activity compared to synthetically derived GABA, demonstrating measurable effects on alpha brain wave patterns, HRV, and subjective relaxation in human studies. As the primary inhibitory neurotransmitter of the central nervous system, GABA supports nervous system downregulation, reduces neuronal excitability, and promotes the grounded, settled state of being that chronic stress disrupts.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eDwarf Morning Glory Root Extract (Evolvulus alsinoides)\u003c\/strong\u003e — A traditional Ayurvedic botanical known as Shankhpushpi, used for centuries in cognitive and nervous system support. Supports memory, mental clarity, and nervous system resilience, providing neuroprotective and calming activity that complements the GABA and serotonin-supporting aspects of the formula.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003e5-HTP (50 mg, from Griffonia simplicifolia seed extract)\u003c\/strong\u003e — A direct precursor to serotonin, the mood-stabilizing and gut-regulating neurotransmitter that chronic stress consistently depletes. 5-HTP bypasses the rate-limiting conversion of tryptophan and is directly converted to serotonin in the brain and gut. Supports mood stability, emotional resilience, healthy appetite regulation, and as a precursor to melatonin, healthy sleep onset when taken in the evening.\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\n\u003cstrong\u003eLiposome Proprietary Blend — 500 mg (Phosphatidylcholine from non-GMO Sunflower Oil, Glycerin Complex, Non-GMO Oleic Acid)\u003c\/strong\u003e — A non-soy phosphatidylcholine liposomal delivery system from sunflower lecithin, forming the phospholipid vesicles that encapsulate the active ingredients for direct mucosal absorption and bypass of digestive degradation. Non-GMO oleic acid provides additional membrane stability.\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cstrong\u003eStorage\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eRefrigerate after opening. Shake gently before use. Keep out of reach of children.\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cstrong\u003eDirections\u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003eTake 15 mL (approximately 3 teaspoons) daily, or as directed by your healthcare provider. May be taken directly or mixed into a beverage of choice. For stress and anxiety support during the day, take with meals. For sleep and relaxation support, take 30 to 60 minutes before bedtime. Chocolate flavored.If you are pregnant, nursing, taking medications, or have a medical condition, consult your healthcare provider before use.\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cem\u003e\u003c\/em\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003e\u003cmeta charset=\"utf-8\"\u003eLiposomal Calm by DesBio is a practitioner-formulated liposomal stress relief supplement available at SOLUDE Wellness \u0026amp; Beauty. It contains Vitamin B6 (as Pyridoxal-5-Phosphate) 1 mg, Glycine 200 mg, and Liposomal Calm Blend 245 mg (L-Theanine, Passionflower Herb Extract, Holy Basil Leaf Extract, GABA as PharmaGABA, Dwarf Morning Glory Root Extract, 5-HTP 50 mg from Griffonia simplicifolia seed extract), in a Liposome Proprietary Blend of 500 mg (Phosphatidylcholine from non-GMO sunflower oil, Glycerin Complex, non-GMO Oleic Acid). It is designed to support healthy GABA activity and nervous system downregulation, serotonin production for mood stability, alpha brain wave activity for calm focused clarity, healthy HPA axis and cortisol regulation via Holy Basil, sleep readiness, and emotional resilience during chronic stress. PharmaGABA for superior bioavailability. Liposomal phosphatidylcholine delivery for rapid absorption. Non-habit forming. Chocolate flavored. Refrigerate after opening. 6 oz bottle, approximately 12 servings at 15 mL daily.\u003c\/em\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003e\u003c\/em\u003e\u003c\/div\u003e\n\u003cdiv class=\"standard-markdown grid-cols-1 grid [\u0026amp;_\u0026gt;_*]:min-w-0 gap-3\"\u003e\u003cem\u003eThese statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"DesBio","offers":[{"title":"Default Title","offer_id":45534221041708,"sku":"SLD-DSB-LCLM-6OZ","price":65.89,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0617\/6122\/4748\/files\/Calm_Liposomal-DesBio.png?v=1778523000","url":"https:\/\/soludebewell.com\/products\/desbio-liposomal-calm-gaba-theanine-5htp-stress-relief","provider":"Solude","version":"1.0","type":"link"}